Poster Presentation The 16th Australian Peptide Conference 2025

Structure-based design, in vitro evaluation and in vivo imaging of a novel peptidomimetic inhibiting the uPA-uPAR interaction (#105)

Esaü Vangeloven 1 2 3 , Sofie Pollenus 3 , Mohsen Hosseini 1 2 , Thomas Dal Maso 2 4 , Sophie Hernot 3 , Wim Versées 2 4 , Steven Ballet 1
  1. Research Group of Organic Chemistry (ORGC), Vrije Universiteit Brussel, Brussels, Belgium
  2. Structural Biology Brussels (SBB), Vrije Universiteit Brussel, Brussels, Belgium
  3. Laboratory for In-vivo Cellular and Molecular Imaging (ICMI), Vrije Universiteit Brussel, Brussels, Belgium
  4. VIB-VUB Center for Structural Biology, Brussels, Belgium
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  1. [1] Smith H. W., Marshall C. J. Nat Rev Mol Cell Biol 2010, 11, 23–36.
  2. [2] Masucci M. T., Minopoli M., Di Carluccio G., Motti M. L., Carriero M. V. Cancers 2022, 14(3), 498
  3. [3] Hernot S., van Manen L., Debie P., Miego J. S. D., Vahrmeijer A. L., Lancet Oncol 2019, 20(7), e354-367
  4. [4] Ploug M., Østergaard S., Gårdsvoll H., Kovalski K., Holst-Hansen C., Holm A., Ossowski L., Danø K. Biochem 2001, 40, 12157-12168
  5. [5] Mateusiak Ł., Floru S., De Groof T. W. M., Wouters J., Declerck N. B., Debie P., Janssen S., Zeven K., Puttemans J., Vincke C., Breckpot K., Devoogdt N,. Hernot S., Adv. Sci. 2024, 11(30), 2400700